HELIC Ammonia Breath Test

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HELIC ABT

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The HELIC ABT with indicator tube is designed for primary noninvasive diagnosis H.pylori infection, as well as for monitoring the status of H.pylori during treatment and for effectiveness checks of therapy which already had been conducted.



Description of the method

  • - HELIC Ammonia Breath Test (HELIC ABT) was designed to exclude pain and discomfort during the diagnostic procedure. HELIC ABT is applied by gastroenterologists, general practitioners, by staff of primary health centers and dispensaries and allows to implement Near Patient Testings (NPT) in any place and situation. No samples need to be sent to a central laboratory.

  • - This is the biochemical method is based on produces a large amount of urease. H.pylori produces a large amount of urease, which degrades urea to ammonia (NH4+). HELIC ABT uses kinetic registration of ammonia concentration in patient’s breath air before and after a portion of unlabelled urea 12C is taken. The value of ammonia level is expressed in color change of indicator composition inside the tube.


Production

HELIC ABT

  • -Plastic indicator tube with urea load

    HELIC ABT












  • - Suction pump

    Suction pump








Short Instruction

Test procedure is very easy. Analysis consists of 2 parts:

  • Part I: Detection of basal level value.Patient to take the tube into his/her mouth. Aspirate the breath air during the period indicated at the label on the pump (6 or 7 minutes).
  • Part II: Detection of load level value after a portion of urea is taken. Ask the patient to take 0,5 g urea dissolved in 50 ml water. After he/she drinks turn the indicator tube the other side and start the second aspiration.


    • When test finished compare the basal level value with the load level value. Count the delta by distracting the basal level value from the load level value.If the delta exceeds the 3 mm, the test is positive; the delta is less than the 3 mm, the test is negative.

Example of color change

  • HP-
    Hp-

  • HP+
    Hp+



Advantages

  • -Immediate result
    The result is available immediately after 15 minutes of the testing.
  • -Safety
    Sensitive sorbent of the test allows doctor to detect H. pylori infection without using radioactive isotope markers. It can be also recommended for pregnant woman and children.
    • -Painless
    Noninvasive procedure. Can be easily applied before and after the therapy course.
  • -Accuracy approved
    The test has proved to be highly sensitive (87%) anf highly specific (91%).
  • -CE
    AMA meets the requirements of the In-vitro Diagnostic Directive 98/79/EC and HELIC ABT is CE mrked.
  • -Easy to store
    Shelf-life is 6 months. No special storage conditions are required.